Ultrabright organic dots with aggregation-induced emission characteristics for real-time two-photon intravital
Dan Ding1, Chi Ching Goh, Guangxue Feng
1Department of Chemical and Biomolecular Engineering, National University of Singapore, 117576, Singapore.
Advanced Materials (Deerfield Beach, Fla.)
|September 17, 2013
Abstract:
Ultrabright organic dots with aggregation-induced emission characteristics (AIE dots) are prepared and shown to exhibit a high quantum yield, a, large two-photon absorption cross-section, and low in vivo toxicity. Real-time two-photon intravital blood vascular imaging in various tissues substantiates that the AIE dots are effective probes for in vivo vasculature imaging in a deep and high-contrast manner.
