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[Epidemiological features on 3 important viral diarrhea among children in Zhuhai during winter and spring]

Ya-Wei Liu1, Wan-Shan Wang, Qiu-Hua Mo

  • 1Medical School of Chinese PLA, Beijing 100853, China.

Zhonghua Shi Yan He Lin Chuang Bing Du Xue Za Zhi = Zhonghua Shiyan He Linchuang Bingduxue Zazhi = Chinese Journal of Experimental and Clinical Virology
|September 19, 2013
PubMed

Insights

Norovirus (NV), sapovirus (SV), and astrovirus (AstV) are significant causes of viral diarrhea in Zhuhai children during winter and spring. Enhanced monitoring of these pathogens in infants and young children is recommended.

Area of Science:

  • Pediatric Infectious Diseases
  • Virology
  • Epidemiology

Context:

  • Viral diarrhea poses a significant health burden on children.
  • Norovirus (NV), sapovirus (SV), and astrovirus (AstV) are common etiological agents of gastroenteritis.
  • Understanding the seasonal and age-specific epidemiology of these viruses is crucial for public health interventions.

Purpose:

  • To investigate the epidemiological characteristics of viral diarrhea caused by NV, SV, and AstV in children in Zhuhai.
  • To determine the prevalence and seasonality of these viral infections during winter and spring.
  • To identify the age groups most affected by these pathogens.

Summary:

  • A study analyzed stool specimens from children with viral diarrhea in Zhuhai between November 2009 and April 2010.
  • Reverse transcription-polymerase chain reaction (RT-PCR) was used to detect NV, SV, and AstV.
  • The overall detection rate was 21.49%, with NV being the most prevalent (14.70%), followed by AstV (4.04%) and SV (2.75%).
  • Children aged 0-30 months accounted for 87.96% of positive cases, with specific age peaks for each virus.
  • All detected NV strains belonged to the G II genogroup.

Impact:

  • Norovirus is identified as a primary cause of viral diarrhea in young children in Zhuhai during the study period.
  • Sapovirus and astrovirus are also recognized as important contributors to pediatric viral gastroenteritis.
  • Findings underscore the need for strengthened surveillance of NV, SV, and AstV in infants and young children to inform prevention and control strategies.
Abstract

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