Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Sleep Apnea01:21

Sleep Apnea

Sleep apnea is a condition where breathing stops intermittently during sleep, often leading to significant health issues. Each episode can last from 10 to 20 seconds or more and is frequently accompanied by a brief arousal from sleep. This disturbance, largely unnoticed by the individual, can lead to severe daytime fatigue. Commonly, individuals seek help after being informed by their partners about loud snoring and noticeable breathing pauses during sleep.
The condition is more prevalent among...
Diabetes: Symptoms, Diagnosis, and Complications01:15

Diabetes: Symptoms, Diagnosis, and Complications

For most patients, experiencing several weeks of polyuria, polydipsia, fatigue, and significant weight loss may indicate the presence of diabetes. Furthermore, adults displaying the phenotypic appearance of type 2 diabetes (particularly those who are obese and not initially insulin-requiring), may have islet cell autoantibodies, suggesting autoimmune-mediated β cell destruction and a diagnosis of latent autoimmune diabetes of adults (LADA). The categorization of glucose homeostasis is based on...
Diabetes Mellitus: Overview and Type I Subtype01:22

Diabetes Mellitus: Overview and Type I Subtype

Diabetes mellitus is a chronic metabolic disorder characterized by high blood glucose levels due to inadequate insulin production, insulin resistance, or both. The condition affects millions worldwide and can significantly impact their health and quality of life.
Type 1 diabetes is an autoimmune disease in which the immune system mistakenly attacks and destroys the insulin-producing beta cells in the pancreas. As a result, the body is unable to produce sufficient insulin, and individuals with...
Diabetes Mellitus: Type 2 and Gestational01:22

Diabetes Mellitus: Type 2 and Gestational

Type 2 diabetes, characterized by insulin resistance, arises when the insulin receptors on cells lose responsiveness to insulin, diminishing the cell's capacity to take up glucose, resulting in elevated blood glucose levels. To receive a diagnosis of Type 2 diabetes, a series of blood glucose tests are necessary to assess whether the blood glucose falls within normal parameters. If the result is out of the normal range, a patient may be diagnosed as prediabetic or diabetic, depending on the...
Type I Diabetes II: Pathophysiology01:26

Type I Diabetes II: Pathophysiology

Type 1 diabetes mellitus arises from an immune-mediated destruction of pancreatic β-cells, resulting in an absolute deficiency of insulin. This process develops in genetically susceptible individuals when autoimmunity, environmental exposures, and immunologic dysregulation converge to trigger a targeted attack on the insulin-producing cells of the pancreas. The β-cells are located within the islets of Langerhans and are essential for regulating blood glucose by facilitating cellular uptake of...
Diabetes Mellitus: Introduction01:26

Diabetes Mellitus: Introduction

Diabetes mellitus consists of chronic metabolic disorders characterized by persistent hyperglycemia. This elevated blood glucose results from defects in insulin secretion, impaired insulin action, or both. Insulin, produced by pancreatic β-cells, is essential for maintaining glucose homeostasis by facilitating cellular glucose uptake for energy or storage. Disruptions in insulin production or function lead to glucose accumulation in the bloodstream, causing the clinical features and long-term...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Explainable Machine Learning for Predicting Dengue Recovery Duration: Insights from Multi-Center Clinical Data.

Healthcare (Basel, Switzerland)·2026
Same author

Gestational weight gain and maternal immediate perinatal and postpartum outcomes in low and middle income countries: individual participant data meta-analyses.

BMJ medicine·2026
Same author

Highly stable photothermal CO<sub>2</sub> conversion to C<sub>2</sub>H<sub>6</sub> with 87% selectivity: cooperative charge redistribution in a heteronuclear catalyst stabilizes the reaction intermediates and enhances C-C coupling.

Materials horizons·2026
Same author

Atomically dispersed cobalt on niobium oxide enables photothermal nitrogen fixation via nitrogen-hydrogen coupling.

Journal of colloid and interface science·2026
Same author

Letter to the Editor on "Clinical profile and optical coherence tomography based morphological characteristics of coronary in-stent restenosis: A cross-sectional study".

Indian heart journal·2026
Same author

Optimized host adaptation to Eri silkworm eggs enhances fitness and biological control efficacy of Trichogramma ostriniae against the Asian corn borer.

Pest management science·2026

Related Experiment Video

Updated: May 7, 2026

Drug-Induced Sleep Endoscopy (DISE) with Target Controlled Infusion (TCI) and Bispectral Analysis in Obstructive Sleep Apnea
07:54

Drug-Induced Sleep Endoscopy (DISE) with Target Controlled Infusion (TCI) and Bispectral Analysis in Obstructive Sleep Apnea

Published on: December 6, 2016

Obstructive sleep apnoea and diabetes: an update.

Abd A Tahrani1, Asad Ali, Martin J Stevens

  • 1aCentre of Endocrinology, Diabetes and Metabolism, University of Birmingham bDepartment of Diabetes and Endocrinology, Heart of England NHS Foundation Trust, Birmingham cDepartment of Respiratory Medicine, University Hospital of Coventry and Warwickshire, Coventry, West Midlands, UK.

Current Opinion in Pulmonary Medicine
|September 20, 2013
PubMed
Summary

Obstructive sleep apnoea (OSA) is linked to insulin resistance and impaired beta-cell function, impacting blood sugar control. Continuous positive airway pressure (CPAP) and lifestyle changes may improve outcomes for patients with type 2 diabetes.

More Related Videos

Acupoint Application Combined with Ear Plaster Therapy for Treating Sleep Disorders with Acute Exacerbation of Chronic Obstructive Pulmonary Disease
04:53

Acupoint Application Combined with Ear Plaster Therapy for Treating Sleep Disorders with Acute Exacerbation of Chronic Obstructive Pulmonary Disease

Published on: October 18, 2024

Auricular Acupuncture as a Traditional Chinese Medicine Therapy for Chronic Obstructive Pulmonary Disease Combined with Sleep Disorders
05:34

Auricular Acupuncture as a Traditional Chinese Medicine Therapy for Chronic Obstructive Pulmonary Disease Combined with Sleep Disorders

Published on: August 18, 2023

Related Experiment Videos

Last Updated: May 7, 2026

Drug-Induced Sleep Endoscopy (DISE) with Target Controlled Infusion (TCI) and Bispectral Analysis in Obstructive Sleep Apnea
07:54

Drug-Induced Sleep Endoscopy (DISE) with Target Controlled Infusion (TCI) and Bispectral Analysis in Obstructive Sleep Apnea

Published on: December 6, 2016

Acupoint Application Combined with Ear Plaster Therapy for Treating Sleep Disorders with Acute Exacerbation of Chronic Obstructive Pulmonary Disease
04:53

Acupoint Application Combined with Ear Plaster Therapy for Treating Sleep Disorders with Acute Exacerbation of Chronic Obstructive Pulmonary Disease

Published on: October 18, 2024

Auricular Acupuncture as a Traditional Chinese Medicine Therapy for Chronic Obstructive Pulmonary Disease Combined with Sleep Disorders
05:34

Auricular Acupuncture as a Traditional Chinese Medicine Therapy for Chronic Obstructive Pulmonary Disease Combined with Sleep Disorders

Published on: August 18, 2023

Area of Science:

  • Endocrinology
  • Sleep Medicine
  • Metabolic Syndrome

Background:

  • Obstructive sleep apnoea (OSA) is increasingly recognized as a significant factor in metabolic health.
  • The interplay between OSA, obesity, and dysglycaemia requires further clarification.
  • Understanding the effects of OSA treatment on glucose metabolism is crucial for managing diabetes.

Purpose of the Study:

  • To review current evidence on the association between obstructive sleep apnoea (OSA) and dysglycaemia.
  • To elucidate the role of obesity as a mediator in the OSA-dysglycaemia relationship.
  • To summarize the impact of OSA treatment on glucose metabolism and its consequences in diabetic patients.

Main Methods:

  • Literature review of recent studies on OSA and dysglycaemia.
  • Analysis of data linking continuous positive airway pressure (CPAP) compliance to insulin resistance.
  • Examination of the correlation between apnoea-hypopnoea index (AHI) during REM sleep and HbA1c levels.

Main Results:

  • OSA is independently associated with insulin resistance and beta-cell dysfunction.
  • Continuous positive airway pressure (CPAP) improves insulin resistance in compliant patients.
  • Nocturnal hypoxaemia in OSA patients with type 2 diabetes correlates with elevated HbA1c, particularly during REM sleep.

Conclusions:

  • OSA contributes to insulin resistance and beta-cell dysfunction, irrespective of obesity.
  • OSA is linked to poorer glycaemic control (HbA1c) and vascular complications in type 2 diabetes.
  • CPAP therapy and lifestyle interventions show potential for improving glycaemic measures and OSA severity.