Related Experiment Video
Updated: May 7, 2026

Treatment Model for Young Patients with Psychogenic Erectile Dysfunction and Resultant Infertility
Published on: May 30, 2025
Is there a relationship between severity of coronary artery disease and severity of erectile dysfunction?
Lutfi Canat1, Gokhan Cicek, Gokhan Atis
1Urology Department, Kastamonu State Hospital, Turkey.
Insights
Erectile dysfunction (ED) severity correlates with the number of blocked arteries in men after myocardial infarction (MI). Hypertension significantly worsens ED in severe coronary artery disease (CAD).
Area of Science:
- Cardiology
- Urology
- Men's Health
Background:
- Erectile dysfunction (ED) is increasingly recognized as a potential predictor of coronary artery disease (CAD).
- The relationship between the extent of coronary artery occlusion and ED severity requires further investigation.
Purpose of the Study:
- To evaluate the association between the number of occluded coronary arteries in myocardial infarction (MI) patients and the severity of ED.
- To investigate the influence of common cardiovascular risk factors on this association.
Main Methods:
- 183 male patients with acute MI undergoing coronary angiography were assessed for erectile functionality.
- Data on age, diabetes, smoking, waist circumference, hypertension, and hematologic parameters were collected.
Main Results:
- 100 out of 183 patients (54.64%) had ED.
- ED prevalence increased with the number of occluded vessels: 45.36% (single-vessel), 64.5% (two-vessel), and 65.7% (three-vessel).
- Hypertension aggravated ED in three-vessel disease; elevated total and LDL cholesterol correlated with lower IIEF scores in single- and two-vessel disease.
Conclusions:
- ED severity is correlated with the number of occluded coronary arteries in male patients with acute MI.
- Hypertension significantly impacts erectile function, particularly in patients with three-vessel coronary artery disease.
Introduction:
The correlation between erectile dysfunction (ED) and coronary artery disease has been emphasized and ED has been recognized as a potential independent risk factor and/or predictor of coronary artery disease (CAD). We evaluated the association between the number of occluded coronary arteries in myocardial infarction (MI) patients with the severity of ED, and investigated the influence of related risk factors in our study group.
Materials And Methods:
183 male patients who underwent coronary angiography because of acute MI from November 2009 to May 2011 were included. Following the stabilization of patients after the treatment, each patient was evaluated for erectile functionality. Risk factors such as age, diabetes, smoking, waist circumference, hypertension, and hematologic parameters were recorded.
Results:
Among 183 patients with a mean age of 55.2 years who underwent coronary angiography due to acute MI, 100 (54.64 %) had ED, while the ED rate was 45.36 % (44/97) in cases of single-vessel disease, 64.5 % (31/48) in cases of two-vessel disease, and 65.7 % (25/38) in cases of three-vessel disease. The mean IIEF score was 24.2 ± 4.3, 20.4 ± 4.9 and 20.5 ± 4.2 for single or two or three-vessel disease, respectively. The presence of hypertension aggravated ED only in patients with three-vessel disease and increased total and LDL cholesterol levels in patients with single-vessel or two-vessel disease were accompanied by significantly decreasing IIEF scores.
Conclusion:
The severity of ED correlated with the number of occluded vessels documented by coronary angiography, in male patients with acute myocardial infarction. In addition, the presence of hypertension had a significant influence over erectile function only in patients with three-vessel occlusion.
Related Concept Videos
Coronary Artery Disease I: Introduction
Coronary Artery Disease II: Pathophysiology
Coronary Artery Disease III: Clinical Manifestations
Coronary Artery Disease V: Interprofessional Care
Coronary Artery Disease IV: Preventive Measures
Ischemic Heart Disease: Overview
Atherosclerosis, the primary malefactor, orchestrates this dangerous condition. It manifests as the accumulation of fatty deposits, akin to insidious plaques, within arterial walls. As time elapses, these plaques metamorphose, hardening and narrowing...