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Updated: May 7, 2026

Catheter Ablation in Combination With Left Atrial Appendage Closure for Atrial Fibrillation
Published on: February 26, 2013
Impact of atrial fibrillation on outcomes in heart failure
Eugene C DePasquale1, Gregg C Fonarow
1Ahmanson-UCLA Cardiomyopathy Center, Division of Cardiology, David Geffen School of Medicine, 100 UCLA Medical Plaza, Suite 630 East, Los Angeles, CA 90095, USA.
Abstract:
The prevalence of atrial fibrillation (AF) and heart failure increases with advancing age. It is estimated that the annual incidence of AF in the general heart failure population is approximately 5%, whereas as many as 40% of patients with advanced heart failure have AF. The goals of therapy in patients with heart failure and AF are symptom control and prevention of arterial thromboembolism. The adverse hemodynamic events of AF may lead to symptom deterioration and reduced exercise capacity. This review addresses the impact of AF on heart failure outcomes as they pertain to prognosis and management.
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