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Interleukin 1: the first interleukin.

F S di Giovine1, G W Duff

  • 1Department of Medicine, University of Edinburgh, UK.

Immunology Today
|January 1, 1990
PubMed
Summary
This summary is machine-generated.

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Interleukin 1 (IL-1) research has surged since 1979, becoming a key focus in biology. This overview highlights IL-1

Area of Science:

  • Immunology
  • Cell Biology
  • Biochemistry

Context:

  • The term 'interleukin' and the designation 'interleukin 1' (IL-1) originated from a 1979 workshop.
  • Interest in IL-1 has grown exponentially, evidenced by increased publications and scientific meetings.
  • IL-1 is recognized as a crucial biological mediator across diverse organ systems.

Purpose:

  • To provide a selective overview of interleukin 1 (IL-1) biology on its tenth anniversary.
  • To highlight the broad impact and scientific interest in IL-1 research.
  • To offer cautionary general points as a backdrop for understanding IL-1 biology.

Summary:

  • Interleukin 1 (IL-1) has garnered significant scientific attention due to its widespread biological roles.
  • Research into IL-1 has expanded rapidly, attracting scientists from various disciplines.

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  • This review focuses on human IL-1, presenting key biological insights and considerations.

    • Impact:

    • Sustained high-level scientific interest in IL-1 biology.
    • Attraction of diverse scientific expertise to the field of IL-1 research.
    • Generation of important and often surprising discoveries regarding IL-1's functions.