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Gold nanorods as multifunctional probes in a liquid crystalline DNA matrix

Joanna Olesiak-Banska1, Marta Gordel, Katarzyna Matczyszyn

  • 1Wroclaw University of Technology, Institute of Physical and Theoretical Chemistry, Wybrzeze Wyspianskiego 27, 50-370 Wroclaw, Poland. joanna.olesiak@pwr.wroc.pl.

Nanoscale
|September 26, 2013
PubMed

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DNA probes are fragments of DNA labeled with a reporter tag to enable their detection or purification. The resulting labeled DNA probes can then hybridize to target nucleic acid sequences through complementary base-pairing, and may be used to recover or identify these regions.
Radioisotopes, fluorophores, or small molecule binding partners like biotin or digoxigenin, are the most widely used reporter tags for labeling DNA probes. These labels can be attached to the probe DNA molecule via...