Related Experiment Video
Updated: May 7, 2026
13:35
Endoscopic Bilateral Nipple-sparing Mastectomy via a Single Axillary Incision with Immediate Pre-pectoral Implant-based Breast Reconstruction
Published on: May 17, 2024
Bilateral breast masses with a rare etiology
Friederike Thieringer1, Gideon Sartorius, Katrin Kalf
1Department of Gynecology and Obstetrics, University Hospital Basel, 4031 Basel, Switzerland.
Case Reports in Oncological Medicine
|September 26, 2013
Summary
This case study highlights a rare presentation of Burkitt's lymphoma involving the breast, ovaries, and suspected bone marrow in a young woman. Prompt polychemotherapy led to a complete and sustained remission.
Area of Science:
- Oncology
- Hematology
- Gynecologic Oncology
Background:
- Breast masses can arise from various benign and malignant causes.
- Burkitt's lymphoma is an aggressive non-Hodgkin lymphoma with diverse presentations.
- Simultaneous involvement of breast and ovaries is an uncommon manifestation of Burkitt's lymphoma.
Purpose of the Study:
- To report a unique case of Burkitt's lymphoma presenting with bilateral breast and ovarian masses.
- To emphasize the importance of recognizing this rare pattern for timely diagnosis and treatment.
- To discuss the management and outcome of this specific presentation.
Main Methods:
- Case presentation of a 28-year-old woman with rapidly developing bilateral breast masses.
- Diagnostic workup including imaging (PET scan), biopsies (ovarian), and cerebrospinal fluid examination.
- Treatment with CODOX-M/IVAC chemotherapy regimen.
Main Results:
- Pathology confirmed Burkitt's lymphoma in bilateral ovarian masses.
- PET scan suggested bone marrow involvement, but bone marrow biopsy was negative.
- The patient achieved a complete response after one cycle of chemotherapy and remained in remission at six months.
Conclusions:
- This is the first reported case of simultaneous breast, ovarian, and suspected bone involvement in Burkitt's lymphoma.
- Gynecologists and oncologists must be vigilant for this rare presentation.
- Rapid initiation of polychemotherapy is crucial for curative intent in such cases.
Related Concept Videos
01:12The Mammary Glands
The female breast is a hemispheric projection of variable size positioned anterior to the pectoralis major and serratus anterior muscles. A fascia layer composed of dense, irregular connective tissue connects it to these muscles.
Each breast features a pigmented projection known as the nipple, through which milk emerges via closely spaced openings of ducts, referred to as lactiferous ducts. Surrounding the nipple is a circular pigmented area of skin named the areola, which appears rough due to...
Each breast features a pigmented projection known as the nipple, through which milk emerges via closely spaced openings of ducts, referred to as lactiferous ducts. Surrounding the nipple is a circular pigmented area of skin named the areola, which appears rough due to...
01:24Disorders of the Female Reproductive System
The female reproductive system can be affected by several disorders, including Premenstrual Syndrome (PMS), Premenstrual Dysphoric Disorder (PMDD), endometriosis, and various forms of cancer. PMS and PMDD are cyclical conditions that cause physical and emotional distress, with symptoms that include edema, mood swings, and food cravings. PMDD is a more severe form of PMS characterized by increased symptom severity that peaks during the luteal phase and tends to improve or resolve shortly after...