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Nephrotoxicity of common drugs used by urologists
1Division of Nephrology and Hypertension, Oregon Health Sciences University, Portland.
The Urologic Clinics of North America
|February 1, 1990
Abstract:
Many clinically popular drugs, such as aminoglycoside antibiotics, amphotericin B, radiographic contrast media, analgesics, platinum-based cancer chemotherapy, and cyclosporine, can cause deterioration of kidney function even when the dose has been adjusted properly for renal insufficiency. The authors review the pathophysiologic mechanisms of nephrotoxicity of these drugs and prevention and treatment strategies.