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A Rodent Model of The Ross Operation: Syngeneic Pulmonary Artery Graft Implantation in A Systemic Position
Published on: April 1, 2022
The Ross procedure: outcomes at 20 years.
Tirone E David1, Carolyn David1, Anna Woo1
1Cardiac Program, Peter Munk Cardiac Centre at Toronto General Hospital and University of Toronto, Toronto, Ontario, Canada.
The Journal of Thoracic and Cardiovascular Surgery
|October 3, 2013
Summary
The Ross procedure offers excellent long-term survival comparable to the general population. However, risks of pulmonary homograft dysfunction and aortic insufficiency require monitoring, especially with dilated aortic annulus.
Area of Science:
- Cardiovascular Surgery
- Thoracic Surgery
- Congenital Heart Disease
Background:
- The Ross procedure is a complex surgical technique for aortic valve disease.
- Long-term outcomes and risk factors for reoperation require further investigation.
Purpose of the Study:
- To evaluate the clinical and echocardiographic outcomes of the Ross procedure.
- To identify risk factors associated with reoperation and valve dysfunction.
Main Methods:
- Prospective follow-up of 212 patients undergoing the Ross procedure.
- Clinical and echocardiographic assessments, including survival analysis and freedom from reoperation.
Main Results:
- 20-year survival was 93.6%, similar to the general population.
- Freedom from reoperation on the pulmonary autograft was 81.8%, and on the pulmonary homograft was 92.7%.
- Aortic insufficiency and pulmonary homograft dysfunction were observed in a significant proportion of patients at 20 years.
Conclusions:
- The Ross procedure demonstrates favorable long-term survival.
- Dilated aortic annulus and preoperative aortic insufficiency increase the risk of developing aortic insufficiency.
- Pulmonary homograft dysfunction is a common long-term complication.
