Related Experiment Video
Updated: May 7, 2026
Thermal Ablation for the Treatment of Abdominal Tumors
Published on: March 7, 2011
Thermal versus impedance-based ablation of renal cell carcinoma: a meta-analysis
Milad Modabber1, Jason Martin, Sriharsha Athreya
1DeGroote School of Medicine, McMaster University, Hamilton, ON, Canada, mmodabber@gmail.com.
Background:
Percutaneous radiofrequency ablation (RFA) of renal carcinoma has become an established treatment modality. However, thermal (TB) versus impedance-based (IB)-RF generators have not been previously compared.
Methods:
A literature search on the application of RFA for renal masses using TB or IB-RF generators was performed. The safety, efficacy, and long-term outcomes of TB versus IB-based RFA were assessed using the outcome measures of technical success, local recurrence rate, complications, and preservation of renal function.
Results:
Across the 27 included studies, pooled results suggested comparable results for technical success (TB-RFA 98.53 % vs. IB-RFA 98.78 %, P = 0.9813). Clinical efficacy results were also similar across both generators (91.0 % TB-RFA vs. 91.5 % IB-RFA; P = 0.73). At follow-up, no differences in renal function (relative risk [RR] 0.5, 95 % confidence interval [CI] 0.45-5.48), and local recurrence (RR 0.717, 95 % CI 0.49-1.50) were observed. The pooled proportion of overall complication rates was 13.1 % for TB-RFA and 11.5 % for IB-RFA.
Conclusion:
No differences in the observed parameters were found either during surgery or at follow-up.
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