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A Machine Learning Approach to Design an Efficient Selective Screening of Mild Cognitive Impairment
12:18

A Machine Learning Approach to Design an Efficient Selective Screening of Mild Cognitive Impairment

Published on: January 11, 2020

Risk factors for the progression of mild cognitive impairment to dementia

Noll L Campbell1, Fred Unverzagt, Michael A LaMantia

  • 1College of Pharmacy, Purdue University, 575 Stadium Mall Drive, West Lafayette, IN 47907, USA; Indiana University Center for Aging Research, 410 West 10th Street, Indianapolis, IN 46202, USA; Regenstrief Institute, Inc, 410 West 10th Street, Indianapolis, IN 46202, USA; Department of Pharmacy, Wishard/Eskenazi Health Services, 1001 West 10th Street, Indianapolis, IN 46202, USA.

Clinics in Geriatric Medicine
|October 8, 2013
PubMed

Insights

Identifying risk factors for mild cognitive impairment (MCI) progression to dementia is crucial for developing interventions. This research highlights key disease markers and modifiable risk factors to reduce dementia

Area of Science:

  • Gerontology
  • Neurology
  • Public Health

Background:

  • Cognitive impairment, including mild cognitive impairment (MCI), is increasingly prevalent in older adults.
  • Progression from MCI to dementia poses a significant public health challenge.

Purpose of the Study:

  • To identify disease progression markers for mild cognitive impairment (MCI).
  • To identify risk factors associated with the progression of MCI to dementia.
  • To explore potentially modifiable risk factors for intervention.

Main Methods:

  • Literature review of studies on MCI and dementia progression.
  • Analysis of identified disease markers and risk factors.
  • Evaluation of potential intervention points for modifiable factors.

Main Results:

  • Several markers indicate disease progression from MCI to dementia.
  • Specific risk factors are linked to accelerated progression.
  • Potentially modifiable risk factors present opportunities for intervention.

Conclusions:

  • Understanding MCI progression markers and risk factors is vital.
  • Targeting modifiable risk factors can help minimize dementia burden.
  • Further research into interventions is warranted.
Keywords:
BiomarkersDementiaGeneticsMild cognitive impairmentRisk factors

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