Infant wheeze: is asthma a possibility?

Philip K Pattemore1

  • 1Department of Paediatrics, University of Otago Christchurch, Christchurch, New Zealand.

Insights

Most infant wheeze cases are not asthma, but asthma can occur in infants. Identifying risk factors and symptoms helps diagnose infant asthma cautiously, especially for severe cases requiring treatment.

Area of Science:

  • Pediatrics
  • Respiratory Medicine
  • Allergology

Background:

  • Infant wheeze is common, but often distinct from asthma.
  • Differentiating asthma from other causes of wheezing in infants is challenging.
  • Infants can exhibit reversible airway obstruction, a feature of asthma.

Purpose of the Study:

  • To clarify the relationship between infant wheeze and asthma.
  • To identify factors aiding in the diagnosis of infant asthma.
  • To guide cautious treatment approaches for suspected infant asthma.

Main Methods:

  • Review of clinical features and risk factors associated with infant wheeze.
  • Analysis of diagnostic challenges in differentiating asthma from other causes.
  • Evaluation of criteria for provisional diagnosis and treatment trials.

Main Results:

  • The majority of infant wheeze cases are not attributed to asthma.
  • Allergic sensitization can be present in infants with reversible airway obstruction.
  • Asthma is a recognized condition in infancy, despite diagnostic complexities.

Conclusions:

  • Diagnosing asthma in infants requires careful consideration of various wheezing causes.
  • Risk factors and clinical presentation are key to a provisional asthma diagnosis.
  • A cautious trial of asthma treatment may be warranted for disabling symptoms.

Related Concept Videos

Asthma I: Introduction01:28

Asthma I: Introduction

Asthma is a chronic inflammatory disorder of the airways characterized by variable airflow obstruction and heightened bronchial responsiveness to a wide range of triggers. The underlying inflammation leads to airway swelling, mucus hypersecretion, and smooth muscle constriction, all of which narrow the airway lumen and impede airflow. Clinically, asthma presents with recurrent episodes of wheezing, shortness of breath, chest tightness, and coughing, symptoms that typically vary in intensity and...
360
Asthma-I: Introduction01:29

Asthma-I: Introduction

Asthma is a chronic respiratory ailment that requires careful management due to its varying symptoms and influencing factors. It is characterized by airway inflammation, bronchial hyperresponsiveness, and reversible airflow obstruction, leading to symptoms like wheezing, shortness of breath, chest tightness, and coughing. The symptom frequency and intensity may vary considerably over time. It is also linked to immune system responses to allergens and irritants, highlighting the complex...
3.6K
Asthma III: Clinical Manifestations01:13

Asthma III: Clinical Manifestations

Asthma presents with a characteristic pattern of episodic respiratory symptoms that reflect underlying airway inflammation, bronchoconstriction, and mucus hypersecretion. Although severity varies among individuals, certain clinical manifestations are considered hallmarks of the disorder and often guide diagnosis and assessment.Respiratory SymptomsA persistent cough is one of the most common early features of asthma. It is frequently dry and tends to worsen at night or in the early morning,...
73
Asthma-III: Symptoms and Complications01:24

Asthma-III: Symptoms and Complications

Asthma, a common chronic respiratory condition, is classified considering the frequency and severity of symptoms alongside lung function impairment. Understanding this classification is essential for appropriate treatment and management. Here's a detailed look at the classification of asthma and its clinical features and complications:
Classification of Asthma
3.5K
Asthma-IV: Diagnostic and Management01:30

Asthma-IV: Diagnostic and Management

The diagnosis and management of asthma are comprehensive, encompassing clinical assessments, lung function tests, and pharmacological interventions. Here's an overview:
Clinical Assessment for Asthma:
This is the first step in diagnosing and managing asthma. It includes:
3.4K
Asthma: Pathogenesis and Management01:20

Asthma: Pathogenesis and Management

Asthma is a chronic pulmonary condition involving inflammation of the airways, hyper-reactivity, and reversible obstruction of the airways. This condition can significantly impact a person's quality of life, making breathing difficult and leading to distressing symptoms.
Asthma is classified as allergic and non-allergic. Allergens such as dust mites, pollen, and pet dander trigger allergic asthma, while factors like cold air, intense emotions, or exercise can induce non-allergic asthma.
1.5K