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Updated: May 7, 2026

A Sample Preparation Pipeline for Microcrystals at the VMXm Beamline
Published on: June 17, 2021
SPring-8 BL41XU, a high-flux macromolecular crystallography beamline
Kazuya Hasegawa1, Nobutaka Shimizu, Hideo Okumura
1SPring-8/JASRI, 1-1-1 Kouto, Sayo, Hyogo 679-5198, Japan.
Abstract:
SPring-8 BL41XU is a high-flux macromolecular crystallography beamline using an in-vacuum undulator as a light source. The X-rays are monochromated by a liquid-nitrogen-cooling Si double-crystal monochromator, and focused by Kirkpatrick-Baez mirror optics. The focused beam size at the sample is 80 µm (H) × 22 µm (V) with a photon flux of 1.1 × 10(13) photons s(-1). A pinhole aperture is used to collimate the beam in the range 10-50 µm. This high-flux beam with variable size provides opportunities not only for micro-crystallography but also for data collection effectively making use of crystal volume. The beamline also provides high-energy X-rays covering 20.6-35.4 keV which allows ultra-high-resolution data to be obtained and anomalous diffraction using the K-edge of Xe and I. Upgrade of BL41XU for more rapid and accurate data collection is proceeding. Here, details of BL41XU are given and an outline of the upgrade project is documented.

