Stem cells-the hidden treasure: A strategic review

Area of Science:

• Biomedical Engineering
• Regenerative Medicine
• Dental Science

Background:

• Organ failure and tissue loss present significant challenges in medical and dental fields.
• Ideal tissue replacement involves using natural, patient-specific tissues or organs.
• Stem cells, including human embryonic stem cells and adult stem cells, show potential for ideal tissue replacement.

Purpose of the Study:

• To explore the potential of stem cells in regenerative dentistry.
• To review recent advancements in dental stem cell research.
• To highlight the applications and future prospects of stem cells in dental tissue regeneration.

Main Methods:

• Isolation of stem cells from various dental sources, including dental pulp, exfoliated deciduous teeth, and apical papilla.
• Review of existing literature on stem cell applications in dentistry.
• Analysis of research outcomes in dentin-pulp and periodontal regeneration.

Main Results:

• Stem cells have been successfully isolated from multiple dental tissue sources.
• Promising results have been observed in dentin-pulp and periodontal regeneration using dental stem cells.
• Ambiguities and limitations still exist, requiring further investigation.

Conclusions:

• Dental stem cells represent a significant advancement in regenerative dentistry.
• Continued research is crucial to overcome current limitations and enable clinical application.
• Stem cell therapy opens new therapeutic avenues for dental tissue repair and regeneration.