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Updated: May 6, 2026

Murine Model of Controlled Cortical Impact for the Induction of Traumatic Brain Injury
Published on: August 16, 2019
Surgical treatment of traumatic injuries of the cranial base
1Division of Head and Neck Oncology, Massachusetts Eye and Ear Infirmary, Massachusetts General Hospital, Harvard Medical School, 243 Charles Street, Boston, MA 02114, USA.
Abstract:
Skull-base fractures involve one or more of the cribriform plate of the ethmoid bone, orbital plate of the frontal bone, sphenoid bone, occipital bone, and petrous or temporal bone. Although the fractures themselves only require reduction and reconstruction when the skull base is severely comminuted and altered, even small fractures and the traumatic shear forces can create tears in the meninges and thus predispose to cerebrospinal fluid leaks. This article explores the preoperative, intraoperative, and postoperative management of skull-base fractures, which most commonly involves resolution of the cerebrospinal fluid leak and the prevention of future leaks or meningoencephaloceles.
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