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Updated: May 6, 2026

Rapid Homogeneous Detection of Biological Assays Using Magnetic Modulation Biosensing System
Published on: June 13, 2010
MRI biosensor for lead detection based on the DNAzyme-induced catalytic reaction
Liguang Xu1, Honghong Yin, Wei Ma
1State Key Lab of Food Science and Technology, School of Food Science and Technology, Jiangnan University , Wuxi, JiangSu 214122, People's Republic of China.
Abstract:
A MRI biosensor for sensitive and specific detection of lead ions (Pb(2+)) was developed based on DNAzyme-induced cleavage of magnetic nanoparticles (MNPs). A low limit of detection (LOD) of 0.05 ng mL(-1) was obtained. This biosensor has the potential to serve as a general platform for the detection of heavy metal ions.
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