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Updated: May 6, 2026

Evaluation of Colorectal Cancer Risk and Prevalence by Stool DNA Integrity Detection
Published on: June 8, 2020
Screening for colorectal cancer: using data to set prevention priorities
Graham A Colditz1, Lucy D'Agostino McGowan, Aimee S James
1Division of Public Health Sciences, Department of Surgery, Alvin J. Siteman Cancer Center, Barnes-Jewish Hospital, Washington University School of Medicine, 660 S. Euclid Avenue, Campus Box 8109, St. Louis, MO, 63110, USA, colditzg@wustl.edu.
Colorectal cancer screening rates vary significantly within Missouri counties, from 25% to 70%. Understanding these disparities is crucial for public health initiatives aimed at increasing screening and reducing cancer deaths.
Area of Science:
- Public Health
- Epidemiology
- Cancer Prevention
Background:
- Colorectal cancer screening adherence varies by state.
- Within-state variability in screening rates is not well understood.
- Targeting public health efforts requires granular screening data.
Purpose of the Study:
- Assess county-level colorectal cancer screening rates in Missouri.
- Identify geographic disparities in screening adherence.
- Inform targeted public health interventions to improve screening rates.
Main Methods:
- Utilized 2008 and 2010 Behavioral Risk Factor Surveillance System data.
- Analyzed screening prevalence in Missouri adults aged 50-74.
- Employed multilevel logistic regression for county-specific estimates.
Main Results:
- Colorectal cancer screening prevalence ranged from 25% to 70% across Missouri counties.
- Significant within-state variability in screening adherence was observed.
- Data represented 78.5% of the state population across 37 counties.
Conclusions:
- State-level screening data masks substantial within-state disparities.
- County-level analysis is essential for effective public health targeting.
- Improved population survey data can enhance future screening analyses.
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