Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Cellular Injury II: Classification01:21

Cellular Injury II: Classification

75
Cellular injury is any process that disrupts a cell’s ability to maintain homeostasis, leading to structural or functional changes. It is broadly classified based on etiology (cause) and mechanism of damage.Classification by EtiologyCellular injury may result from several causes. Hypoxic injury happens due to reduced oxygen delivery, most commonly from inadequate blood supply, such as arterial obstruction; for example, coronary artery thrombosis can cause myocardial infarction. Chemical...
75
Classification of Epithelial Tissues: Overview01:22

Classification of Epithelial Tissues: Overview

24.2K
Epithelial tissues are classified according to the shape of the cells and the number of cell layers formed. Cell shapes can be squamous (flattened and thin), cuboidal (square-like, as wide as it is tall), or columnar (rectangular, taller than it is wide). Additionally, the nucleus shape helps identify the type of epithelial cells. Squamous cells have flattened disc-shaped nuclei, cuboidal cells have spherical nuclei, and columnar cells have elongated nuclei.
Based on the number of cell layers,...
24.2K
Cellular Injury IV: Necrosis01:16

Cellular Injury IV: Necrosis

97
Necrosis is a form of irreversible cell death caused by severe injury such as ischemia, toxins, or trauma. Unlike programmed cell death, it is an uncontrolled, pathological process that typically provokes inflammation in surrounding tissues.Pathophysiologic ChangesNecrosis begins when cells sustain critical damage, leading to swelling of organelles, particularly mitochondria, and rapid ATP depletion. As energy levels decline, membrane ion pumps fail, leading to calcium influx and eventually,...
97
Cellular Injury IlI: Cellular Death01:11

Cellular Injury IlI: Cellular Death

93
Cell death is the irreversible loss of cellular structure and function, representing the final stage of severe injury. It plays a key role in both normal physiology and disease.Types of Cell DeathThe two main types are necrosis and apoptosis, though others like necroptosis and pyroptosis also exist.Necrosis:Necrosis is an unregulated form of cell death caused by severe injury such as trauma, toxins, or ischemia. It is characterized by cell swelling, membrane loss, rupture, and leakage of...
93
Tissue Homogenization and Cell Lysis01:32

Tissue Homogenization and Cell Lysis

9.0K
Tissue homogenization involves disintegrating tissue architecture and lysing cells, and is an early step in isolating and analyzing cellular components. The method used for homogenization depends on the sample type, the amount of sample available, the analyte to be obtained, and the sensitivity of the method. These methods are broadly classified as mechanical and non-mechanical methods.
Mechanical methods of tissue homogenization
These methods rely on applying external physical force to disrupt...
9.0K
Tissues01:25

Tissues

63.9K
Tissues are a group of cells that share a common embryonic origin. Microscopic observation reveals that the cells in a tissue share morphological features and are arranged in an orderly pattern to perform specific functions. From an evolutionary perspective, tissues appear in more complex organisms. Although there are many types of cells in the human body, they are organized into four broad categories of tissues: epithelial, connective, muscle, and nervous. Each of these categories is...
63.9K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Proposed addendum to the 2006 US Food and Drug Administration guidance on chronic cutaneous ulcers and burn wounds: recommendations from the Wound Care Collaborative Community.

Wounds : a compendium of clinical research and practice·2026
Same author

Advancing chronic wound care with near-infrared spectroscopy imaging: clinical applications, measurement parameters, and insights into healing dynamics.

Wounds : a compendium of clinical research and practice·2025
Same author

An overview and survey of US Food and Drug Administration-registered wound imaging devices capable of determining percentage area reduction and/or percentage volume reduction.

Wounds : a compendium of clinical research and practice·2025
Same author

Textile composition, not number of layers, impacts interphase pressure and static stiffness index: A pragmatic, comparative analysis of the in vivo interphase pressure of 7 different 2-layer cohesive bandage kits in healthy volunteers.

Wound management & prevention·2023
Same author

Microgravity and Lymphatics: Why Space Programs Need Lymphedema Physiology Specialists.

Lymphatic research and biology·2023
Same author

Selecting appropriate compression for lymphedema patients: American Vein and Lymphatic Society position statement.

Phlebology·2023

Related Experiment Video

Updated: May 6, 2026

Renal Ischaemia Reperfusion Injury: A Mouse Model of Injury and Regeneration
12:27

Renal Ischaemia Reperfusion Injury: A Mouse Model of Injury and Regeneration

Published on: June 7, 2014

50.1K

Tissue destruction classification systems.

Holly Korzendorfer1, Pamela Scarborough, Heather Hettrick

  • 1Holly Korzendorfer, PhD, PT, CWS, FACCWS, is Vice President of Business and Clinical Development at DermaRite Industries, LLC, Paterson, New Jersey. Pamela Scarborough, DPT, MS, PT, CDE, CWS, CEEAA, is Director of Public Policy and Education at American Medical Technologies, Irvine, California. Heather Hettrick, PhD, PT, CWS, FACCWS, MLT, DAPWCA, is Associate Professor at Nova Southeastern University, Ft. Lauderdale, Florida.

Advances in Skin & Wound Care
|October 24, 2013
PubMed
Summary
This summary is machine-generated.

Classifying wound tissue destruction is complex. This article reviews established wound classification systems to aid clinicians in accurately assessing tissue damage.

More Related Videos

Systematic Scoring Analysis for Intestinal Inflammation in a Murine Dextran Sodium Sulfate-Induced Colitis Model
09:11

Systematic Scoring Analysis for Intestinal Inflammation in a Murine Dextran Sodium Sulfate-Induced Colitis Model

Published on: February 14, 2021

9.2K
Tissue Characterization after a New Disaggregation Method for Skin Micro-Grafts Generation
09:30

Tissue Characterization after a New Disaggregation Method for Skin Micro-Grafts Generation

Published on: March 4, 2016

20.9K

Related Experiment Videos

Last Updated: May 6, 2026

Renal Ischaemia Reperfusion Injury: A Mouse Model of Injury and Regeneration
12:27

Renal Ischaemia Reperfusion Injury: A Mouse Model of Injury and Regeneration

Published on: June 7, 2014

50.1K
Systematic Scoring Analysis for Intestinal Inflammation in a Murine Dextran Sodium Sulfate-Induced Colitis Model
09:11

Systematic Scoring Analysis for Intestinal Inflammation in a Murine Dextran Sodium Sulfate-Induced Colitis Model

Published on: February 14, 2021

9.2K
Tissue Characterization after a New Disaggregation Method for Skin Micro-Grafts Generation
09:30

Tissue Characterization after a New Disaggregation Method for Skin Micro-Grafts Generation

Published on: March 4, 2016

20.9K

Area of Science:

  • Wound healing and tissue repair
  • Clinical assessment of injuries

Background:

  • Accurate wound assessment is crucial for effective treatment planning.
  • Clinicians face challenges in consistently classifying tissue destruction levels.
  • Existing classification systems can be confusing and require clarification.

Purpose of the Study:

  • To present and clarify established wound classification systems.
  • To provide clinicians with tools for accurate wound damage assessment.
  • To reduce confusion in classifying the extent of tissue destruction.

Main Methods:

  • Review of existing literature on wound classification systems.
  • Comparative analysis of different wound assessment criteria.
  • Synthesis of information to provide clear guidance.

Main Results:

  • Multiple wound classification systems exist, each with specific criteria.
  • Understanding these systems aids in differentiating wound severity.
  • Standardized classification improves diagnostic accuracy.

Conclusions:

  • Clearer understanding of wound classification systems enhances clinical practice.
  • Accurate assessment of tissue destruction leads to better patient outcomes.
  • Further standardization may improve inter-observer reliability.