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Updated: Feb 22, 2026

Generation of a Mouse Spontaneous Autoimmune Thyroiditis Model
Published on: March 17, 2023
Cutaneous lymphoid hyperplasia mimicking cutaneous lymphoma in a hyperthyroid cat
Elisabeth Snead1, Moira Kerr, Valerie Macdonald
1Department of Small Animal Clinical Sciences (Snead, MacDonald), Prairie Diagnostic Services (Kerr), Western College of Veterinary Medicine, University of Saskatchewan, 52 Campus Drive, Saskatoon, Saskatchewan S7N 5B4.
Abstract:
A 12-year-old neutered male domestic shorthair cat presented for chronic, localized, swelling and crusting of the left upper lip, weight loss, sporadic vomiting, and focal alopecia between the scapulae was diagnosed with hyperthyroidism and regional eosinophilic lymphadenitis. Treatment with methimazole exacerbated an underlying hypersensitivity disorder leading to marked generalized lymphadenopathy that histologically mimicked lymphoma.

