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Optimized Management of Endovascular Treatment for Acute Ischemic Stroke
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Optimized Management of Endovascular Treatment for Acute Ischemic Stroke

Published on: January 18, 2018

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Endovascular treatment of intracranial atherosclerotic disease

Christopher J Lenart1, Mandy J Binning, Erol Veznedaroglu

  • 1Stroke and Cerebrovascular Center of New Jersey, 750 Brunswick Avenue, Trenton, NJ 08638, USA.

Neuroimaging Clinics of North America
|October 26, 2013
PubMed

Insights

Stroke, a leading cause of death, involves intracranial atherosclerosis. While treatments like stenting show promise for severe cases, the best approach for symptomatic intracranial atherosclerotic disease remains under debate.

Area of Science:

  • Neurology
  • Vascular Medicine
  • Interventional Cardiology

Background:

  • Stroke is a major cause of mortality in the US.
  • Intracranial atherosclerotic disease contributes significantly to cerebrovascular accidents.
  • Established risk factors for this condition are well-documented.

Purpose of the Study:

  • To review the current understanding and treatment of intracranial atherosclerosis.
  • To evaluate the evolution of medical and endovascular therapies.
  • To address the ongoing debate regarding the optimal management of symptomatic intracranial atherosclerotic disease.

Main Methods:

  • Review of existing literature on intracranial atherosclerosis treatments.
  • Analysis of outcomes from medical, surgical bypass, and endovascular therapies.
  • Examination of initial reports on stent placement for high-grade disease.

Main Results:

  • Surgical bypass has not demonstrated superiority over medical therapy.
  • Endovascular therapies have evolved, including the use of cardiac devices.
  • Initial stent placement reports for symptomatic high-grade disease were encouraging.

Conclusions:

  • The optimal treatment for symptomatic intracranial atherosclerotic disease is still debated.
  • Medical and endovascular approaches continue to evolve.
  • Further research is needed to establish definitive treatment guidelines.

Keywords:
AtherosclerosisEndovascular treatmentIschemic strokeRisk factors

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