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Updated: May 6, 2026

Retinal Vascular Reactivity as Assessed by Optical Coherence Tomography Angiography
Published on: March 26, 2020
Changes in optical coherence tomography findings in acute zonal occult outer retinopathy
Shinji Makino1, Hironobu Tampo
1Department of Ophthalmology, Jichi Medical University, Shimotsuke, Japan.
Purpose:
To report a case of acute zonal occult outer retinopathy (AZOOR) in a 39-year-old woman.
Methods:
Images were obtained with fundus photography and optical coherence tomography (OCT). A multifocal electroretinogram (mfERG) was also obtained to evaluate retinal function.
Results:
The patient's right visual acuity was 0.8. Fundus photographs showed no specific abnormal findings. OCT showed attenuation of the photoreceptor inner segment/outer segment (IS/OS) line and the cone outer segment tip (COST) line in the right eye. The mfERG showed corresponding amplitude reductions. One month after the initial visit, her right visual acuity improved to 1.2. There was partial recovery of the IS/OS line; however, the COST line was still absent, and there was no apparent improvement in the mfERG responses.
Conclusions:
Our findings showed a discrepancy between the microstructural findings and visual function during recovery of AZOOR.

