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Complications associated with oral anticoagulation therapy
1Emergency Services, University of Kentucky Chandler Medical Center, Lexington.
Advanced Emergency Nursing Journal
|November 2, 2013
Summary
Advanced practice nurses (APNs) should be aware that gastrointestinal bleeding is a common complication of oral anticoagulation therapy, particularly with dabigatran and warfarin. This review highlights best evidence for managing these anticoagulant-related bleeding risks.
Area of Science:
- Pharmacology
- Clinical Nursing
- Evidence-Based Practice
Background:
- Oral anticoagulation therapy is crucial for preventing thromboembolic events.
- Managing complications, especially bleeding, is a key responsibility for advanced practice nurses (APNs).
- Recent evidence requires translation into practical clinical guidance for APNs.
Purpose of the Study:
- To review current evidence on complications associated with oral anticoagulation therapy.
- To provide practical guidance for APNs in managing these complications.
- To utilize a case study module for effective knowledge translation.
Main Methods:
- A comprehensive review of recent scientific evidence.
- Development of a case study module focused on oral anticoagulation complications.
- Analysis of bleeding complication rates associated with specific anticoagulants.
Main Results:
- Gastrointestinal bleeding was the most frequent complication of oral anticoagulation.
- Dabigatran (80%) and warfarin (48%) were associated with high rates of gastrointestinal bleeding.
- The findings underscore the significant bleeding risks inherent in these therapies.
Conclusions:
- APNs must be vigilant in monitoring patients for gastrointestinal bleeding during oral anticoagulation.
- Evidence-based strategies are essential for mitigating anticoagulant-related bleeding risks.
- Integrating case study learning enhances APN preparedness in managing complex anticoagulation scenarios.
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