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Updated: May 6, 2026

Utilization of Microscale Silicon Cantilevers to Assess Cellular Contractile Function In Vitro
Published on: October 3, 2014
Stochastic switching of cantilever motion
Warner J Venstra1, Hidde J R Westra, Herre S J van der Zant
1Kavli Institute of Nanoscience, Delft University of Technology, Lorentzweg 1, Delft 2628CJ, The Netherlands.
Abstract:
The cantilever is a prototype of a highly compliant mechanical system and has an instrumental role in nanotechnology, enabling surface microscopy, and ultrasensitive force and mass measurements. Here we report fluctuation-induced transitions between two stable states of a strongly driven microcantilever. Geometric nonlinearity gives rise to an amplitude-dependent resonance frequency and bifurcation occurs beyond a critical point. The cantilever response to a weak parametric modulation is amplified by white noise, resulting in an optimum signal-to-noise ratio at finite noise intensity. This stochastic switching suggests new detection schemes for cantilever-based instrumentation, where the detection of weak signals is mediated by the fluctuating environment. For ultrafloppy, cantilevers with nanometer-scale dimensions operating at room temperature--a new transduction paradigm emerges that is based on probability distributions and mimics nature.
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