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Electrical and mechanical office-based neuromodulation
Ravi Kacker1, Aaron Lay, Anurag Das
1Division of Urology, Beth Israel Deaconess Medical Center, Harvard Medical School, 330 Brookline Avenue, Boston, MA 02215, USA.
The Urologic Clinics of North America
|November 5, 2013
Summary
Overactive bladder (OAB) treatments include conservative methods and medications. When these fail, sacral neuromodulation and percutaneous tibial nerve stimulation offer effective, FDA-approved alternatives for OAB symptom relief.
Area of Science:
- Urology
- Neurology
Background:
- Overactive bladder (OAB) is a prevalent condition in urologic practice.
- Current treatment pathways start with conservative measures and antimuscarinic pharmacotherapy.
- A subset of patients experiences inadequate symptom control or intolerable side effects from pharmacotherapy.
Purpose of the Study:
- To review the role of neuromodulation techniques in OAB management.
- To highlight sacral neuromodulation and percutaneous tibial nerve stimulation as subsequent treatment options.
Main Methods:
- Review of current treatment algorithms for overactive bladder.
- Discussion of office-based neuromodulation techniques: sacral neuromodulation and percutaneous tibial nerve stimulation.
Main Results:
- Sacral neuromodulation and percutaneous tibial nerve stimulation are established next steps in OAB care.
- These techniques provide efficacious treatment for overactive bladder symptoms.
Conclusions:
- Neuromodulation techniques, including sacral neuromodulation and percutaneous tibial nerve stimulation, are effective and FDA-approved options for patients with OAB.
- These methods offer viable alternatives for patients unresponsive to or intolerant of initial therapies.

