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Updated: May 6, 2026

Traction Microscopy Integrated with Microfluidics for Chemotactic Collective Migration
Published on: October 13, 2019
Collective cell migration: a mechanistic perspective
Sri Ram Krishna Vedula1, Andrea Ravasio, Chwee Teck Lim
11Mechanobiology Institute, National University of Singapore, Singapore;
Abstract:
Collective cell migration is fundamental to gaining insights into various important biological processes such as wound healing and cancer metastasis. In particular, recent in vitro studies and in silico simulations suggest that mechanics can explain the social behavior of multicellular clusters to a large extent with minimal knowledge of various cellular signaling pathways. These results suggest that a mechanistic perspective is necessary for a comprehensive and holistic understanding of collective cell migration, and this review aims to provide a broad overview of such a perspective.
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