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Healthy live birth using theophylline in a case of retrograde ejaculation and absolute asthenozoospermia
Thomas Ebner1, Omar Shebl1, Richard Bernhard Mayer1
1Abteilung für Gynäkologische Endokrinologie und Kinderwunsch Zentrum, Landes, Frauen, und Kinderklinik, Austria.
Objective:
To analyze whether the use of ready-to-use theophylline is a feasible option in a case of retrograde ejaculation and absolute asthenozoospermia.
Design:
Case report.
Setting:
In vitro fertilization unit of a public hospital.
Patient(S):
Thirty-one-year-old nulliparous woman, and 39-year-old male with retrograde ejaculation and absolute asthenozoospermia.
Intervention(S):
Retrieval of postejaculatory urine, restoration of motility using a methylxanthine, intracytoplasmic sperm injection, single-embryo transfer.
Main Outcome Measure(S):
Sperm motility, fertilization, embryo quality, live birth.
Result(S):
Successful fertilization and a single-embryo transfer resulted in a healthy live birth.
Conclusion(S):
Theophylline turned out to be a safe, efficient agent for stimulating immotile spermatozoa in patients with retrograde ejaculation.
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