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Updated: May 6, 2026

05:37
Single-Molecule Fluorescence Visualization of DNA Polymerase Dynamics at G-Quadruplexes
Published on: April 4, 2025
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Pyrene-imidazolium complexed graphene for the selective fluorescent detection of G-quadruplex forming DNA
Seung Jin Moon1, So Hyeon Park, Justyn Jaworski
1Department of Chemistry and Research Institute of Natural Sciences, Gyeongsang National University, Jinju, South Korea. jonghwa@gnu.ac.kr.
Abstract:
A unique system has been developed for quantifying G-quadruplex forming DNA down to picomolar levels for future applications in telomeric assessment. Pyrene-imidazolium captured in high amounts on the surface of reduced graphene oxide shells allows specific DNA sequence detection by complex formation resulting in release and fluorescence enhancement of pyrene-imidazolium.

