Related Experiment Video
Updated: May 6, 2026
09:21
Optimized Management of Endovascular Treatment for Acute Ischemic Stroke
Published on: January 18, 2018
14.4K
[Interventional prevention of ischemic stroke]
1Unité de cathétérisme cardiaque, service d'explorations fonctionnelles, centre hospitalier Henri-Mondor, Assistance publique-Hôpitaux de Paris, 51, avenue du Maréchal-de-Lattre-de-Tassigny, 94000 Créteil, France.
Annales De Cardiologie Et D'Angeiologie
|November 9, 2013
Summary
Stroke prevention in atrial fibrillation is crucial. Left atrial appendage closure offers a promising alternative to anticoagulation for patients at high risk of stroke or bleeding.
Area of Science:
- Cardiology
- Neurology
- Medical Devices
Context:
- Stroke is a leading cause of disability and death, necessitating effective prevention strategies.
- Atrial fibrillation significantly increases stroke risk, requiring careful patient management.
- Current treatments like anticoagulation have limitations for certain patient groups.
Purpose:
- To review the role of left atrial appendage percutaneous closure as an alternative stroke prevention strategy.
- To evaluate the feasibility, effectiveness, and safety of devices like WATCHMAN(©), PLAATO, and AmplatzerCardiacPlug™.
- To discuss the implications of studies like PROTECT-AF and ongoing clinical evaluations.
Summary:
- Left atrial appendage (LAA) percutaneous closure is an emerging interventional treatment for stroke prevention in atrial fibrillation.
- Devices such as WATCHMAN(©) have demonstrated non-inferiority to warfarin in preventing thromboembolic events.
- Risk stratification using CHA(2)DS(2)VASc and HASBLED scores guides treatment decisions.
Impact:
- Provides a potential alternative for patients unsuitable for or experiencing complications with anticoagulation.
- Offers a new therapeutic avenue to reduce the burden of stroke in atrial fibrillation patients.
- Highlights the need for further research to define optimal patient selection for LAA closure.
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