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Ischemic Stroke l: Introduction

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Updated: May 6, 2026

Optimized Management of Endovascular Treatment for Acute Ischemic Stroke

Optimized Management of Endovascular Treatment for Acute Ischemic Stroke

Published on: January 18, 2018

[Interventional prevention of ischemic stroke].

P Kamtchueng¹, E Teiger

¹Unité de cathétérisme cardiaque, service d'explorations fonctionnelles, centre hospitalier Henri-Mondor, Assistance publique-Hôpitaux de Paris, 51, avenue du Maréchal-de-Lattre-de-Tassigny, 94000 Créteil, France.

Annales De Cardiologie Et D'Angeiologie

|November 9, 2013

Summary

Stroke prevention in atrial fibrillation is crucial. Left atrial appendage closure offers a promising alternative to anticoagulation for patients at high risk of stroke or bleeding.

Keywords:

Accident vasculaire cérébral Atrial fibrillation Auricule gauche Bleeding risk Fermeture percutanée Fibrillation auriculaire Left atrium appendage Oral anticoagulant therapy Percutaneous closure Risque hémorragique Stroke Traitement anticoagulant

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A Thrombotic Stroke Model Based On Transient Cerebral Hypoxia-ischemia

A Thrombotic Stroke Model Based On Transient Cerebral Hypoxia-ischemia

Published on: August 18, 2015

Area of Science:

Cardiology
Neurology
Medical Devices

Context:

Stroke is a leading cause of disability and death, necessitating effective prevention strategies.
Atrial fibrillation significantly increases stroke risk, requiring careful patient management.
Current treatments like anticoagulation have limitations for certain patient groups.

Purpose:

To review the role of left atrial appendage percutaneous closure as an alternative stroke prevention strategy.
To evaluate the feasibility, effectiveness, and safety of devices like WATCHMAN(©), PLAATO, and AmplatzerCardiacPlug™.
To discuss the implications of studies like PROTECT-AF and ongoing clinical evaluations.

Summary:

Left atrial appendage (LAA) percutaneous closure is an emerging interventional treatment for stroke prevention in atrial fibrillation.
Devices such as WATCHMAN(©) have demonstrated non-inferiority to warfarin in preventing thromboembolic events.
Risk stratification using CHA(2)DS(2)VASc and HASBLED scores guides treatment decisions.

Impact:

Provides a potential alternative for patients unsuitable for or experiencing complications with anticoagulation.
Offers a new therapeutic avenue to reduce the burden of stroke in atrial fibrillation patients.
Highlights the need for further research to define optimal patient selection for LAA closure.