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Published on: August 14, 2019
Influenza vaccination in kids, are you kidding me?
Inge Ahout1, Gerben Ferwerda, Ronald de Groot
1Department of Pediatrics, Laboratory of Pediatric Infectious Diseases, Nijmegen, The Netherlands.
Insights
Routine influenza vaccination for children is debated for inclusion in national programs. This review examines current evidence on pediatric influenza vaccines against Dutch criteria for new vaccine introductions.
Area of Science:
- Virology
- Immunology
- Public Health
Background:
- Seasonal influenza causes significant annual disease burden globally.
- Influenza vaccines are available and widely used in pediatric and adult populations.
- The inclusion of routine pediatric influenza vaccination in national immunization programs is under consideration.
Purpose of the Study:
- To review current data on the efficacy and safety of influenza vaccines in children.
- To evaluate the evidence for routine pediatric influenza vaccination.
- To assess this evidence against the Dutch criteria for introducing new vaccines into the National Immunization Program (NIP).
Main Methods:
- Literature review of influenza viruses and available vaccines.
- Analysis of current epidemiological and clinical data on pediatric influenza vaccination.
- Comparative assessment against established national immunization program criteria.
Main Results:
- Discussion of influenza virus characteristics and vaccine technologies.
- Presentation of available data on the effectiveness and safety of pediatric influenza vaccination.
- Evaluation of the evidence in the context of the Dutch NIP introduction criteria.
Conclusions:
- The review provides a framework for evaluating the evidence for routine pediatric influenza vaccination.
- Findings will inform the decision-making process regarding the inclusion of pediatric influenza vaccination in the Dutch NIP.
- Further discussion is needed to weigh the benefits against the criteria for national program implementation.
Abstract:
Seasonal influenza infections cause a high burden of disease for the whole community every year. Effective vaccines are available and used worldwide in adults and children. Discussion is ongoing as to whether influenza vaccination for children should be implemented in the National Immunization Program (NIP). Is there enough evidence to support routine influenza vaccination in children? In this review we briefly discuss the influenza viruses and the available vaccines. Subsequently, the current data available on influenza vaccination is reviewed and weighed against the Dutch criteria for the introduction of new vaccines into the NIP.
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