Related Experiment Video
Updated: May 6, 2026
08:03
In Vivo Mouse Model of Spinal Implant Infection
Published on: June 23, 2020
2.5K
Stump infections after major lower-limb amputation: a 10-year retrospective study
H Dutronc1, A Gobet, F-A Dauchy
1Service de maladies infectieuses et tropicales, hôpital Pellegrin, place Amélie-Raba-Léon, 33076 Bordeaux cedex, France.
Medecine Et Maladies Infectieuses
|November 12, 2013
Summary
Managing lower-limb stump infections requires accurate bacteriological data and multidisciplinary care. Prompt treatment allows most patients to use prostheses successfully.
Area of Science:
- Infectious Diseases
- Surgical Management
- Orthopedics
Background:
- Limited published data exists on managing lower-limb stump infections.
- Focus excludes toe and forefoot amputations.
Purpose of the Study:
- To review diagnostic and therapeutic strategies for post-surgical lower-limb stump infections.
- To identify factors influencing treatment outcomes.
Main Methods:
- Retrospective observational study of 72 patients with major lower-limb amputations.
- Infection diagnosis and treatment management analyzed from January 2000 to December 2009.
Main Results:
- Stump infections diagnosed >6 weeks post-amputation in 50% of cases.
- Staphylococcus was the most common pathogen.
- Combined imaging (ultrasound, CT, fistulography) aided diagnosis.
- 44% required surgical revision; bone infections necessitated more surgery (P<0.001).
Conclusions:
- Reliable bacteriological documentation (abscess aspiration or bone biopsy) is crucial for targeted antibiotic therapy.
- Multidisciplinary approach involving surgeons, rehabilitation specialists, and infectious disease physicians is optimal.
- Successful infection treatment enables prosthesis use for most patients.
