Laser induced fluorescence spectroscopy for detection of erlikh adenocarcinoma (a pilot study)

Current diagnostic methods, including computed tomography (CT), magnetic resonance imaging (MRI), and endoscopic ultrasound (EUS), have not been able to provide accurate diagnosis in early stage disease, either by failing to identify small lesions or accurately differentiating masses as adenoma or cancer. On the other hand, optical spectroscopic techniques examine different types of light-tissue interactions and provide biochemical and morphological information that can be used to characterize changes that take place as tissues become diseased. The combined use of intrinsic fluorescence, diffuse reflectance and light scattering spectroscopy yields complementary information which can be used to detect even precancers. The aim of our study was to evaluate the effectiveness of laser examination in diagnose of oral mucosa tumors. This method gives us possibility of precise diagnostic in just few minutes. Our pilot survey has shown the efficacy of using laser induced fluorescence (LIF) spectroscopy for diagnostic oral mucosa pathology.