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Subacute rhinitis in infants: gastroesophageal reflux must be considered
1Department of Otorhinolaryngology, St John Grande's Hospital, Kraków, Poland.
Insights
Gastroesophageal reflux disease (GERD) significantly impacts infant subacute rhinitis, worsening symptoms. Treatment with nasal glucocorticoids and lifestyle changes effectively reduced nasal secretions and feeding difficulties in infants with GERD.
Area of Science:
- Pediatrics
- Otolaryngology
- Gastroenterology
Background:
- Subacute rhinitis in infants presents diagnostic challenges.
- Gastroesophageal reflux disease (GERD) is a potential contributing factor to infant respiratory and feeding issues.
Purpose of the Study:
- To investigate the role of GERD and allergies in infant subacute rhinitis.
- To evaluate the efficacy of different treatment regimens for subacute rhinitis in infants.
Main Methods:
- Seventy-four infants diagnosed with subacute rhinitis were assessed using the Infant Gastroesophageal Reflux Questionnaire Revised.
- Infants with confirmed GERD were randomly assigned to receive fluorometholone nasal drops with positional/feeding adjustments, only positional/feeding adjustments, or a placebo for 10 days.
Main Results:
- Treatment with nasal glucocorticoids combined with positional and feeding changes led to significant reductions in nasal secretions (75.9%), swallowing difficulty (79.2%), and uneasiness (92.0%).
- These improvements were significantly greater than those observed with positional and feeding changes alone.
- The placebo group showed no improvement, and the influence of nasal allergy was not statistically significant.
Conclusions:
- GERD may exacerbate subacute rhinitis in infants, suggesting a link between gastrointestinal and respiratory symptoms.
- Targeting GERD through appropriate interventions can alleviate symptoms of subacute rhinitis in affected infants.
Objectives:
The study sought to evaluate the influence of gastroesophageal reflux disease (GERD) and allergy on subacute rhinitis in infants.
Methods:
Mothers of 74 infants with subacute rhinitis completed the Infant Gastroesophageal Reflux Questionnaire Revised. Participants with GERD were randomized to undergo one of the following regimens for 10 days: use of fluorometholone nasal drops with positional and feeding changes; positional and feeding changes; or a placebo.
Results:
The daily amount of nasal secretion decreased by 75.9% (p < 0.001), the intensity of swallowing difficulty by 79.2% (p < 0.001), and the incidence of uneasiness by 92.0% (p < 0.001) in infants treated with nasal glucocorticoid and positional and feeding changes; and the percentage differences in the amount of nasal secretion (p < 0.001), feeding difficulty (p < 0.001), and uneasiness (p < 0.001) were greater than those in the group treated with positional and feeding changes. The infants treated with placebo did not improve. The influence of nasal allergy was nonsignificant.
Conclusions:
Gastroesophageal reflux disease might contribute to aggravation of subacute rhinitis in infants.
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