Related Experiment Video

Updated: May 5, 2026

Basophil Activation Test for Allergy Diagnosis
07:22

Basophil Activation Test for Allergy Diagnosis

Published on: May 31, 2021

10.0K

Pediatric urticaria

Teresa Tsakok1, George Du Toit, Carsten Flohr

  • 1Guy's and St Thomas' Hospital NHS Foundation Trust, King's College London, London SE1 7EH, UK.

Immunology and Allergy Clinics of North America
|November 23, 2013
PubMed

Insights

Pediatric urticaria significantly impacts children's quality of life. This review offers clinicians an evidence-based approach to managing childhood hives, covering presentation, diagnosis, and treatment.

Area of Science:

  • Pediatric dermatology
  • Allergy and immunology

Background:

  • Urticaria, commonly known as hives, affects children's quality of life.
  • It is crucial for clinicians to have evidence-based guidelines for managing pediatric urticaria.

Purpose of the Study:

  • To provide clinicians with a comprehensive, evidence-based approach to pediatric urticaria.
  • To assess current literature on the presentation, natural history, investigation, and management of childhood hives.

Main Methods:

  • Systematic literature search of online databases, including Medline.
  • Review of studies on pediatric urticaria management.
  • Inclusion of an illustrative case study.

Main Results:

  • Highlighted challenges faced by patients, families, and clinicians.
  • Summarized studies on disease management in children.
  • Assessed the current understanding of pediatric urticaria.

Conclusions:

  • Pediatric urticaria requires careful management due to its impact on quality of life.
  • An evidence-based approach is essential for effective diagnosis and treatment.
  • Further understanding of this condition is needed.

Keywords:
Evidence-based approachPediatric urticariaQuality of lifeUrticaria

More Related Videos

Precision Implementation of Minimal Erythema Dose MED Testing to Assess Individual Variation in Human Inflammatory Response06:31

Precision Implementation of Minimal Erythema Dose MED Testing to Assess Individual Variation in Human Inflammatory Response

Published on: October 3, 2019

8.2K
Granulocyte-dependent Autoantibody-induced Skin Blistering12:23

Granulocyte-dependent Autoantibody-induced Skin Blistering

Published on: October 12, 2012

9.9K

Related Concept Videos

Allergic Reactions: Anaphylaxis01:30

Allergic Reactions: Anaphylaxis

Anaphylaxis is a severe, life-threatening hypersensitivity reaction mediated by Immunoglobulin E (IgE) antibodies. When IgE binds to allergens, it triggers the release of mediators– histamine, leukotrienes, and prostaglandins from mast cells and basophils. These mediators cause vasodilation, edema, and inflammation, leading to various symptoms.The primary allergens causing anaphylaxis include food items (e.g., peanuts, shellfish), drugs (e.g., penicillin, asparaginase, corticotropin,...
293
Drug Toxicity: Allergic Reactions01:30

Drug Toxicity: Allergic Reactions

Drug-related allergies are immune-mediated responses triggered by the administration of pharmacological agents. These hypersensitivity reactions are classified based on the immune mechanisms involved. The four primary types—Type I, II, III, and IV—are mediated by different immunological pathways and exhibit distinct clinical manifestations.Type I Hypersensitivity/ IgE-Mediated Reactions: Immunoglobulin E (IgE) immediately mediates Type I hypersensitivity reactions. Upon initial...
223
Pharmacokinetics in Pediatric Patients: Drug Metabolism01:24

Pharmacokinetics in Pediatric Patients: Drug Metabolism

In pediatric care, understanding the nuances of hepatic drug metabolism is crucial, as it significantly differs from that of adults. This divergence is primarily due to the developmental stage of drug-metabolizing enzymes, which affects how medications are processed in the body. In neonates, for instance, the activity of Phase I enzymes—critical for the initial breakdown of drugs—is markedly reduced, functioning at just 20–40% of the levels seen in adults. This reduction poses...
414
Pharmacokinetics in Pediatric Patients: Drug Excretion01:26

Pharmacokinetics in Pediatric Patients: Drug Excretion

In pediatric medicine, understanding the renal function and drug elimination nuances is crucial for administering safe and effective treatments. Newborns, in particular, display markedly slower renal functions than adults, profoundly affecting how drugs are cleared from their bodies. This slower drug clearance requires clinicians to extend the dosing intervals for many medications to prevent drug accumulation and toxicity while ensuring therapeutic efficacy.One key area where these adjustments...
413
Drug Dosing: Infants and Children01:29

Drug Dosing: Infants and Children

Pediatric patient dosages diverge from adults due to disparities in body surface area, total body water, and extracellular fluid per kilogram of body weight. The dosing regimen considers the variations in pharmacokinetics and pharmacology across distinct age groups, encompassing preterm newborns, infants, young children, older children, and adolescents. Calculation of pediatric patient doses is predicated on determining body surface area, which exhibits a superior correlation with the child's...
1.0K
Allergic Reactions02:06

Allergic Reactions

Overview
26.7K