Current cancer therapies - a guide for perioperative physicians
Johannes M Huitink1, Wendy H L Teoh
1Department of Anaesthesiology, VU University Medical Center/VUmc Cancer Center Amsterdam, De Boelelaan 1117, 1081 HV Amsterdam, The Netherlands.
Best Practice & Research. Clinical Anaesthesiology
|November 26, 2013
Summary
Modern cancer treatments improve survival but can cause complications. This review discusses the perioperative effects of chemotherapy, radiotherapy, and experimental therapies, offering guidance for optimal patient management.
Area of Science:
- Oncology
- Anesthesiology
- Surgical Oncology
Background:
- Cancer remains a leading global cause of mortality.
- Advances in anti-cancer therapies enhance patient survival rates.
- These therapies can introduce significant perioperative complications and toxicity.
Purpose of the Study:
- To review the perioperative effects of contemporary cancer treatments.
- To discuss the implications of chemotherapy, radiotherapy, and experimental therapies on anesthesia.
- To summarize common and rare complications and provide management recommendations.
Main Methods:
- Literature review of modern anti-cancer therapies.
- Analysis of perioperative considerations for anesthesia in cancer patients.
- Synthesis of data on treatment-related complications.
Main Results:
- Chemotherapy, radiotherapy, and experimental agents present unique anesthetic challenges.
- Understanding potential toxicities and complications is crucial for patient safety.
- Optimal perioperative management requires a multidisciplinary approach.
Conclusions:
- Effective management of cancer patients undergoing surgery necessitates a thorough understanding of treatment-related risks.
- Anesthesiologists and oncologists must collaborate to mitigate perioperative morbidity.
- Evidence-based guidelines are essential for optimizing outcomes in this complex patient population.
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