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Tumor Progression

Tumor Progression

Tumor progression is a phenomenon where the pre-formed tumor acquires successive mutations to become clinically more aggressive and malignant. In the 1950s, Foulds first described the stepwise progression of cancer cells through successive stages.
Colon cancer is one of the best-documented examples of tumor progression. Early mutation in the APC gene in colon cells causes a small growth on the colon wall called a polyp. With time, this polyp grows into a benign, pre-cancerous tumor. Further...

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Related Experiment Video

Updated: May 5, 2026

Coculture Assays to Study Macrophage and Microglia Stimulation of Glioblastoma Invasion

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Published on: October 20, 2016

CD97 and glioma invasion

Li-Chun Huang¹, Dueng-Yuan Hueng

¹Tri-Service General Hospital, National Defense Medical Center, Taipei, Taiwan.

Journal of Neurosurgery

|November 30, 2013

Summary

No abstract available in PubMed .

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