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Updated: May 5, 2026

Flow-sorting and Exome Sequencing of the Reed-Sternberg Cells of Classical Hodgkin Lymphoma
Published on: June 10, 2017
Customized targeted therapy in Hodgkin lymphoma: hype or hope?
Catherine Diefenbach1, Ranjana Advani
1Department of Medicine, New York University School of Medicine/New York University Cancer Center, 240 East 38th Street, New York, NY 10016, USA.
Abstract:
Although most patients with Hodgkin lymphoma (HL) are cured with primary therapy, patients with primary refractory disease or relapse after initial treatment have poor outcomes and represent an unmet medical need. Recent advances in unraveling the biology of HL have yielded a plethora of novel targeted therapies. This review provides an overview of the data behind the hype generated by these advances and addresses the question of whether or not clinically these targeted therapies offer hope for patients with HL.
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