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Prophylactic antibiotics in otolaryngologic surgeries: from knowledge to practice
Minoo Khatami-Moghadam1, Mohammad-Taghi Khorsandi-Ashtiani, Mohammad-Ali Mohagheghi
1Otorhinolaryngology Research Center, Tehran University of Medical Sciences, Amir-Alam University Hospital.
Iranian Journal of Otorhinolaryngology
|December 5, 2013
Summary
Prophylactic antibiotic use in head and neck surgeries was significantly misused in a hospital setting. Overuse was observed in both pre- and post-operative antibiotic administration, indicating a need for improved clinical practice guidelines.
Area of Science:
- Medical Research
- Clinical Pharmacy
- Surgical Oncology
Background:
- Antimicrobial drug management has significant clinical, economic, and environmental implications.
- Antimicrobials are frequently prescribed, necessitating rational antibiotic attitudes in healthcare policy.
- This study investigated antibiotic prophylaxis in head and neck surgeries.
Purpose of the Study:
- To evaluate the current practices of antibiotic prophylaxis in head and neck surgeries.
- To identify potential areas of misuse or overuse of prophylactic antibiotics.
- To inform healthcare policy regarding rational antibiotic use.
Main Methods:
- Retrospective case series design.
- Data collected from patients undergoing otolaryngology surgeries at a tertiary referral center.
- Questionnaires administered by unaware staff to gather data on patient condition, procedures, and antibiotic regimens.
Main Results:
- 1349 patients requiring prophylactic antibiotics were studied.
- 37.0% received pre-operative parenteral antibiotics, predominantly cephalosporins (94.9%).
- All patients received post-operative antibiotics, averaging 4.81 doses, mainly cephalosporins.
Conclusions:
- Significant misuse of prophylactic antibiotics was identified in a university hospital setting.
- Physician education on prophylaxis principles is crucial.
- Translating prophylaxis knowledge into clinical practice is paramount.
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