Related Experiment Video
Updated: May 5, 2026

In vivo and In vitro Infection of Potato Roots with Plant Parasitic Nematodes for the Assessment of Induced Structural Changes
Published on: February 28, 2025
Detoxification function of geophagy and domestication of the potato
1Division of Biological Sciences and Museum of Anthropology, University of Michigan, 48109, Ann Arbor, Michigan.
Abstract:
Detoxification as the adaptive function of geophagy is demonstrated from field and historical data associating clay consumption with the domestication of potentially toxic potatoes. In vitro analyses showed that the glycoalkaloid, tomatine, was effectively adsorbed by four classes of edible clays over a range of simulated gastrointestinal conditions. These results, in conjunction with reports of geophagy by nonhuman primates, suggest geophagy as a solution to the impasse chemical deterrents pose to the process of domestication and to chemical constraints on plant exploitation by non-fireusing hominids. The inorganic component of the chemical environment deserves increased attention from chemical ecologists.
Related Concept Videos
Enhanced Elimination of Poison
Antidotes serve a crucial role in counteracting the effects of poison by inhibiting enzymes responsible for producing harmful drug metabolites. In some cases, these toxic metabolites can be neutralized by endogenous cosubstrates, which are maintained at specific concentrations to prevent interaction with cellular macromolecules and subsequent cell death.
Renal excretion is the...
Physiology of the Gastrointestinal System III: Elimination
Prevention of Further Absorption of Poison
Overview of Metabolism
Plant Metabolism
Sunlight, the primary source of energy in plants, is first absorbed by the chlorophyll pigments present in their leaves. Plants then use this energy to carry out photosynthesis, where water is oxidized into oxygen and carbon dioxide...
Autophagy
An autophagic pathway consists of a series of signaling events activated in response to diverse stress and physiological conditions such as food deprivation,...
Phase II Reactions: Miscellaneous Conjugation Reactions
A key example involves the conjugation of cyanide ions, which impair cellular respiration and alter hemoglobin into non-oxygen-carrying cyanmethemoglobin. To neutralize this threat, a sulfur atom from thiosulphate is transferred to the cyanide ion, catalyzed by the enzyme rhodanese, resulting in an inactive compound called thiocyanate. The production of...

