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Updated: May 5, 2026

The Multiple Sclerosis Performance Test MSPT: An iPad-Based Disability Assessment Tool
Published on: June 30, 2014
Cognition, cognitive dysfunction, and cognitive rehabilitation in multiple sclerosis.
Mary Pepping1, Julie Brunings, Myron Goldberg
1Department of Rehabilitation Medicine, University of Washington School of Medicine, Box 356490, 1959 Northeast Pacific Street, Seattle, WA 98195, USA.
This study reviews cognitive rehabilitation strategies for multiple sclerosis (MS), detailing neuropsychological changes and evaluation methods. It emphasizes improving daily function through targeted cognitive retraining approaches.
Area of Science:
- Neuroscience
- Rehabilitation Medicine
- Clinical Psychology
Background:
- Multiple sclerosis (MS) frequently causes neurocognitive and neurobehavioral changes impacting daily life.
- Understanding the specific patterns of preserved and disrupted cognitive functions in MS is crucial for effective intervention.
Purpose of the Study:
- To outline effective cognitive rehabilitation approaches for individuals with multiple sclerosis (MS).
- To describe the neurobiological underpinnings of cognitive changes in MS.
- To emphasize the importance of comprehensive evaluations in tailoring cognitive retraining.
Main Methods:
- Review of neuropsychological function patterns in MS.
- Description of relevant brain anatomy and physiology related to cognitive changes.
- Highlighting the role of multidisciplinary evaluations (neuropsychological, speech-language pathology, clinical) in treatment design.
Main Results:
- Common neurocognitive deficits in MS include impairments in memory, attention, and executive functions.
- Preserved cognitive functions can be leveraged to support rehabilitation efforts.
- Comprehensive assessments guide the personalization of cognitive retraining programs.
Conclusions:
- Effective cognitive rehabilitation for MS requires understanding individual cognitive profiles and underlying neurobiology.
- Multidisciplinary assessment is essential for developing targeted and effective cognitive retraining strategies.
- Cognitive rehabilitation aims to mitigate the functional impact of MS-related cognitive impairments, enhancing daily performance.
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