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Lipoma arborescens successfully treated with (90)Y synovectomy
Jim O'Doherty1, Ralf Clauss, James Scuffham
1From the *Department of Medical Physics-Nuclear Medicine, Royal Surrey County Hospital, Guildford; †Division of Imaging Sciences, PET Imaging Centre at St Thomas' Hospital, King's College London, London; and Departments of ‡Nuclear Medicine, and §Rheumatology, Royal Surrey County Hospital, Guildford, United Kingdom.
Radionuclide therapy using Y-citrate colloid offers a novel treatment for lipoma arborescens (LA) in the knee. This study demonstrates successful volume reduction of bilateral knee lipoma arborescens with localized Yttrium-90 treatment.
Area of Science:
- Orthopedics
- Nuclear Medicine
- Radiology
Background:
- Lipoma arborescens (LA) is a benign synovial proliferation in the knee joint.
- Data on radionuclide therapy for knee lipoma arborescens is limited.
- This study explores Yttrium-90 citrate colloid as a treatment for bilateral LA.
Observation:
- A rare case of bilateral lipoma arborescens in the knees was treated.
- SPECT/CT imaging assessed radiopharmaceutical biodistribution.
- Yttrium-90 citrate colloid showed localized distribution around the lipoma arborescens.
Findings:
- Successful treatment of bilateral knee lipoma arborescens was achieved.
- SPECT/CT confirmed localized radiocolloid retention around the lipoma arborescens.
- MRI scans revealed significant reduction in lipoma arborescens volume post-treatment.
Implications:
- Radionuclide therapy with Yttrium-90 citrate colloid is a viable treatment option for lipoma arborescens.
- This minimally invasive approach offers potential for joint preservation.
- Further research is warranted to establish efficacy and safety in larger cohorts.
