Related Experiment Video
Updated: May 5, 2026

Y-90 Radioembolization and PD-1 Inhibitor as Neoadjuvant Treatment in Hepatocellular Carcinoma
Published on: May 24, 2024
Lipoma arborescens successfully treated with (90)Y synovectomy
Jim O'Doherty1, Ralf Clauss, James Scuffham
1From the *Department of Medical Physics-Nuclear Medicine, Royal Surrey County Hospital, Guildford; †Division of Imaging Sciences, PET Imaging Centre at St Thomas' Hospital, King's College London, London; and Departments of ‡Nuclear Medicine, and §Rheumatology, Royal Surrey County Hospital, Guildford, United Kingdom.
Abstract:
Lipoma arborescens (LA) in the knee is a benign intra-articular lipomatous proliferation of the synovial membrane, and data on treatment of LA by radionuclide therapy is sparse. We present a rare case of bilateral LA in the knees successfully treated with injection of Y-citrate colloid. We assessed the biodistribution of the radiopharmaceutical through the use of SPECT/CT imaging. Our images show slight redistribution of the radiocolloid in the knee joint, whereas most of the radioactivity remains localized around the LA. MRI scans confirmed the efficacy of this treatment, with a significant reduction in LA volume after 6 months.
