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Related Experiment Videos

Clinical experience with an activity sensing pacemaker.

F W Lindemans, I R Rankin, R Murtaugh

    Pacing and Clinical Electrophysiology : PACE
    |November 1, 1986
    PubMed
    Summary
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    The Medtronic Activitrax pacemaker

    Area of Science:

    • Cardiology
    • Biomedical Engineering
    • Clinical Trials

    Background:

    • Pacemakers are crucial for managing bradyarrhythmias.
    • The Medtronic Activitrax pacemaker offers rate-responsive pacing.
    • Evaluating new pacemaker technologies is essential for patient care.

    Purpose of the Study:

    • To assess the clinical performance of the Medtronic Activitrax pacemaker.
    • To compare the Activity mode with standard VVI/AAI pacing modes.
    • To evaluate patient outcomes and exercise capacity.

    Main Methods:

    • Worldwide multicenter study involving 222 patients.
    • Data collected on implant, follow-up, and pacing indications.
    • Paired treadmill tests and 24-hour Holter monitoring were conducted.

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  • Patient-reported symptom scores were used to assess daily life impact.

    • Main Results:

    • Activity mode significantly increased heart rate and exercise time compared to VVI/AAI mode (p < 0.0001).
    • Patients with exclusively paced rhythms showed similar improvements with Activity mode.
    • 24-hour Holter recordings confirmed appropriate rate modulation during daily activities.
    • Patients reported fewer problems with physical effort in Activity mode (p < 0.05).

    Conclusions:

    • The Medtronic Activitrax pacemaker, in Activity mode, enhances exercise capacity and improves daily life for patients.
    • Rate-responsive pacing provides significant benefits over fixed-rate pacing.
    • This study supports the efficacy of the Activitrax pacemaker for indicated patients.