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In vivo Reprogramming of Adult Somatic Cells to Pluripotency by Overexpression of Yamanaka Factors
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[Pluripotency and induced nuclear reprogramming in vertebrates: new perspectives]

Pierluigi Scerbo1, Laurent Coen2

  • 1Institut de Biologie du Développement de Marseille Luminy, CNRS UMR 7288, case 907, campus de Luminy, 13009 Marseille, France - Département Régulations, Développement et Diversité Moléculaire, CNRS UMR 7221, Muséum National d'Histoire Naturelle (MNHN), CP No. 32, 7 rue Cuvier, 75231 Paris Cedex 5, France.

Biologie Aujourd'Hui
|December 17, 2013
PubMed
Summary

Pluripotency, the ability of cells to become any cell type, is crucial in development. This review explores molecular regulation, evolution, and clinical applications of pluripotent stem cells, including in vivo reprogramming.

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