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In Vitro release from reverse poloxamine/α-cyclodextrin matrices: modelling and comparison of dissolution profiles

Eneko Larrañeta1, Cristina Martínez-Ohárriz, Itziar Vélaz

  • 1Departamento de Química y Edafología, Facultad de Ciencias, Universidad de Navarra, Pamplona, Navarra, 31080, Spain.

Journal of Pharmaceutical Sciences
|December 17, 2013
PubMed
Summary

Biocompatible gels and tablets made from Tetronic 90R4 and alpha-cyclodextrin (α-CD) show sustained drug release. These matrices are effective for delivering both small molecules like L-tryptophan and proteins such as BSA.

Keywords:
controlled releasecyclodextrinsgelsmathematical modelsprotein delivery

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