[Prognostic value of D-dimer fibrin level in neurosurgical patients before elective hospitalization]

Deep vein thrombosis and pulmonary embolism in postoperative period are very dangerous complications for patient with any surgical pathology. Frequency of deep vein thrombosis in neurosurgical patient can be up to 25-30%. D-dimer level is considered as one of the most reliable indicator of thrombosis. We measured D-dimer level before hospitalization for elective surgery in 4052 patients with different neurosurgical pathology. It was found clear correlation with elevated D-dimer level and frequency of ultrasound signs of thrombosis. In patients with simultaneous presence of elevated D-dimer level and external signs of varicose veins diagnosis was confirmed by ultrasound in every cases. We consider that D-dimer can be reliable screening method for assessment the risk of thrombosis in neurosurgical patients in preoperative period.