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Updated: May 4, 2026
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Murine Kidney Transplant Technique
Published on: October 20, 2015
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Mucormycosis of the transplanted kidney with renal papillary necrosis
Krishan L Gupta1, Kusum Joshi, Ashok Bhat
1Department of Nephrology, Postgraduate Institute of Medical Education and Research, Chandigarh, 160 012 India.
Abstract:
The occurrence of renal allograft mucormycosis is uncommon, but its association with renal papillary necrosis has not been reported. We describe such an association in a patient who survived on peritoneal dialysis after nephrectomy and antifungal therapy.
Insights
Renal allograft mucormycosis is rare, but this study reports its association with renal papillary necrosis for the first time. The patient recovered with antifungal treatment and peritoneal dialysis after kidney removal.
Area of Science:
- Nephrology
- Infectious Diseases
- Transplantation Immunology
Background:
- Renal allograft mucormycosis is an infrequent but serious fungal infection.
- Renal papillary necrosis is a known complication of various renal pathologies.
- The co-occurrence of these conditions in kidney transplant recipients is not previously documented.
Observation:
- A case of renal allograft mucormycosis presenting with renal papillary necrosis is described.
- The patient underwent nephrectomy (surgical removal of the kidney) and received antifungal therapy.
- The patient's post-operative management included peritoneal dialysis.
Findings:
- This report details the first documented association between renal allograft mucormycosis and renal papillary necrosis.
- Successful management involved a combination of surgical intervention, antifungal treatment, and supportive renal replacement therapy.
- The patient demonstrated a positive outcome, surviving with peritoneal dialysis.
Implications:
- This case highlights the importance of considering mucormycosis in transplant recipients with unusual renal complications.
- Early recognition and multidisciplinary management are crucial for improving outcomes in such rare scenarios.
- Further research may elucidate the pathogenic mechanisms linking mucormycosis and renal papillary necrosis in allografts.
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