Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

X-ray Imaging

X-ray Imaging

German physicist Wilhelm Röntgen (1845–1923) was experimenting with electrical current when he discovered that a mysterious and invisible "ray" would pass through his flesh but leave an outline of his bones on a screen coated with a metal compound. In 1895, Röntgen made the first durable record of the internal parts of a living human: an "X-ray" image (as it came to be called) of his wife’s hand. Scientists worldwide quickly began their own experiments with...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Machine Learning for Coronary Heart Disease Prediction: Comparative Analysis of Framingham and Cleveland Subset of the UCI Dataset with SHAP-Based Interpretability.

Epidemiologia (Basel, Switzerland)·2026

Same author

Corrigendum to "Integrated multiplex PCR and metatranscriptomics reveal upper-lower airway microbial landscapes in pediatric respiratory infections" [Virol. Sin. 41 (2026) 58-69].

Virologica Sinica·2026

Same author

Enantioselective Synthesis of Atropisomeric 1,3-Dienes via Platinum-Catalyzed Hydrosilylation of 1,3-Enynes.

Angewandte Chemie (International ed. in English)·2026

Same author

DeDiAttack: Enhancing Transferability of Unrestricted Adversarial Examples via Deformation-Constrained Diffusion.

Sensors (Basel, Switzerland)·2026

Same author

Inhibition of protein kinase CK2 remodels the tumor immune microenvironment and sensitizes lung cancer to PD-L1 blockade.

Experimental hematology & oncology·2026

Same author

Downregulation of LANCL1 exacerbates jaundice-induced liver injury by enhancing oxidative stress and hepatocyte apoptosis.

Biochemical and biophysical research communications·2026

Same journal

From Geometry to Intensity: A Coarse-to-Fine Pipeline for Unsupervised 3D Ultrasound Stitching.

Proceedings of SPIE--the International Society for Optical Engineering·2026

Same journal

AVA: Automated Viewability Analysis for Ureteroscopic Intrarenal Surgery.

Proceedings of SPIE--the International Society for Optical Engineering·2026

Same journal

Kidney Endoscopy Video to Preoperative CT Alignment for Depth Estimation.

Proceedings of SPIE--the International Society for Optical Engineering·2026

Same journal

Deep learning‑based cell type prediction in lung tissue from brightfield histology using CODEX-derived labels.

Proceedings of SPIE--the International Society for Optical Engineering·2026

Same journal

Reconstructing physiological signals from fMRI across the adult lifespan.

Proceedings of SPIE--the International Society for Optical Engineering·2026

Same journal

Axially Swept Light-Sheet Microscopy using scattering and fluorescence contrast mechanisms.

Proceedings of SPIE--the International Society for Optical Engineering·2026

See all related articles

Search research articles

Related Experiment Video

Updated: May 4, 2026

Expedited Radiation Biodosimetry by Automated Dicentric Chromosome Identification ADCI and Dose Estimation

Expedited Radiation Biodosimetry by Automated Dicentric Chromosome Identification ADCI and Dose Estimation

Published on: September 4, 2017

Graphical User Interface for a Dual-Module EMCCD X-ray Detector Array.

Weiyuan Wang¹, Ciprian Ionita¹, Andrew Kuhls-Gilcrist¹

¹University at Buffalo (State University of New York), Toshiba Stroke Research Center, 3435 Main St., Buffalo, NY 14214, USA.

Proceedings of Spie--The International Society for Optical Engineering

|December 21, 2013

Summary

This summary is machine-generated.

A new Graphical User Interface (GUI) enhances a Solid State X-ray Image Intensifier (SSXII) system for improved medical imaging. This advanced system, utilizing Electron-Multiplying CCDs (EMCCDs), offers high resolution and sensitivity for better diagnostics.

Keywords:

Electron-Multiplying CCD (EMCCD)Graphical User Interface Image Guided Interventions Laboratory Virtual Instrumentation Engineering Workbench (LabVIEW)Solid State X-ray Image Intensifier (SSXII)System

More Related Videos

Visualization of Low-Level Gamma Radiation Sources Using a Low-Cost, High-Sensitivity, Omnidirectional Compton Camera

Visualization of Low-Level Gamma Radiation Sources Using a Low-Cost, High-Sensitivity, Omnidirectional Compton Camera

Published on: January 30, 2020

X-ray Dose Reduction through Adaptive Exposure in Fluoroscopic Imaging

X-ray Dose Reduction through Adaptive Exposure in Fluoroscopic Imaging

Published on: September 11, 2011

Related Experiment Videos

Last Updated: May 4, 2026

Expedited Radiation Biodosimetry by Automated Dicentric Chromosome Identification ADCI and Dose Estimation

Expedited Radiation Biodosimetry by Automated Dicentric Chromosome Identification ADCI and Dose Estimation

Published on: September 4, 2017

Visualization of Low-Level Gamma Radiation Sources Using a Low-Cost, High-Sensitivity, Omnidirectional Compton Camera

Visualization of Low-Level Gamma Radiation Sources Using a Low-Cost, High-Sensitivity, Omnidirectional Compton Camera

Published on: January 30, 2020

X-ray Dose Reduction through Adaptive Exposure in Fluoroscopic Imaging

X-ray Dose Reduction through Adaptive Exposure in Fluoroscopic Imaging

Published on: September 11, 2011

Area of Science:

Medical Imaging Technology
Digital Radiography
X-ray Detection Systems

Background:

Traditional X-ray detectors face limitations in resolution and sensitivity for advanced imaging.
Readout noise can degrade image quality in high-sensitivity X-ray imaging applications.
Enlarging the field-of-view (FOV) is crucial for comprehensive radiographic and fluoroscopic examinations.

Purpose of the Study:

To develop a user-friendly Graphical User Interface (GUI) for a novel Solid State X-ray Image Intensifier (SSXII) system.
To enhance the control and image acquisition capabilities of an EMCCD-based X-ray detector array.
To facilitate improved visualization of small anatomical structures and medical devices in radiographic and fluoroscopic procedures.

Main Methods:

Development of a GUI using Laboratory Virtual Instrumentation Engineering Workbench (LabVIEW).
Integration of an array of Electron-Multiplying CCDs (EMCCDs) with variable on-chip gain.
Implementation of image stitching to create a large FOV (2k×1k pixels) image.
Control of camera parameters such as exposure time, trigger mode, and EMCCD gain.

Main Results:

The GUI enables patient registration, module control, image acquisition, and review.
The SSXII system achieves image acquisition rates of 17 Hz at 2k×1k resolution.
The system allows for easy adjustment of common camera parameters and patient image navigation.
The modular design supports future expansion for even larger FOVs.

Conclusions:

The developed GUI significantly improves the usability of the EMCCD-based SSXII imager.
The high-resolution, high-sensitivity system enhances visualization of small vessels and devices.
This technology has the potential to improve diagnostic accuracy and precision in image-guided interventions.