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Updated: May 4, 2026
08:01
Detection of Invasive Pulmonary Aspergillosis in Haematological Malignancy Patients by using Lateral-flow Technology
Published on: March 22, 2012
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A hematologic condition expressed as a lung disease
Mónica Egozcue-Dionisi1, José Nieves-Nieves1, Ricardo Fernández-Gonzalez1
1Pulmonary Medicine Department, San Juan City Hospital, San Juan, Puerto Rico.
F1000Research
|December 24, 2013
Summary
Multiple myeloma rarely causes myelomatous pleural effusion, a complication associated with poor prognosis. This case highlights the rarity and poor outcomes of this condition in multiple myeloma patients.
Area of Science:
- Oncology
- Pulmonology
- Hematology
Background:
- Multiple myeloma is a plasma cell malignancy.
- Pleural involvement is an uncommon complication, occurring in about 1% of patients.
- Myelomatous pleural effusion indicates a poor prognosis.
Purpose of the Study:
- To report a rare case of myelomatous pleural effusion in a multiple myeloma patient.
- To emphasize the poor prognostic implications of this complication.
Main Methods:
- Case presentation of a 39-year-old male with a history of multiple myeloma.
- Clinical evaluation including physical examination, chest radiography, and pleural fluid analysis.
- Analysis of abnormal plasma cells in pleural fluid.
Main Results:
- The patient presented with dyspnea, cough, and chest pain.
- Chest radiogram confirmed a right-sided pleural effusion.
- Pleural fluid analysis showed abundant abnormal plasma cells.
- The patient died four weeks after hospitalization.
Conclusions:
- Myelomatous pleural effusion is a rare but significant complication of multiple myeloma.
- Its presence is a poor prognostic indicator, regardless of disease stage.
- Currently, no definitive treatment improves survival for this condition.
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